Bioburden Testing Services

With thorough testing, we make sure your products meet the highest industry standards.

Introduction to Bioburden Testing Services

Bioburden testing has numerous applications in various industries, especially in sectors where the safety and quality of a product are of utmost importance. Whether it’s pharmaceuticals, medical devices or personal care products, the presence of microorganisms can pose significant risks. Therefore, accurate and reliable bioburden testing is of immense importance in preventing contamination and retaining product integrity.

What is Bioburden testing?

Bioburden testing represents a type of microbiological testing that detects and measures the number of viable microorganisms present in either products, surfaces, or raw materials before sterilization. Bioburden testing gives a clear picture to manufacturers about the potential contamination risks in their products.

Bioburden testing is important, since it gives critical information whether the manufacturing process is appropriately controlled to minimize the presence of microorganisms. This test is, therefore, one of the cornerstones of quality control processes in industries dealing with pharmaceuticals, medical devices, and food production, where contamination might lead to either product failure or be harmful to consumer health. It must be noted that, bioburden testing is done before sterilization or during final product processing, and thus forms a preventative approach toward quality assurance programs.

Our Bioburden testing services

Our bioburden testing services include the detection and quantification of viable microorganisms by membrane filtration, pour plate and direct inoculation methods, ensuring accurate quantification of microbial load in your products or materials.

Compliance and standards

At MIS, we provide bioburden testing services that align with international standards to ensure that your products meet the regulatory requirements and best practices of various industries. Some of the key standards followed at MIS include the following: 

  • ISO 11737-1
    This international standard covers the requirements to determine the bioburden of medical devices. Guidelines for the preparation, conducting and reporting of bioburden tests are outlined in this standard to ensure that the sterility of the product is maintained.
  • ISO 11137
    Provides guidelines on radiation sterilization processes for the medical device industry.
  • USP <1227>
    The USP guidelines for bioburden testing in pharmaceutical products ensure at every step that the microbial load in the raw and finished product remains within acceptable limits.
  • USP 1111
    This standard establishes the microbial quality guidelines for non-sterile products, ensuring that they do not exceed specified microbial limits.
  • USP 60
    USP 60 specifies microbial analysis methods for the presence or absence of Burkholderia cepacia Complex in non–sterile medical products.
  • USP 61
    The standard explains the microbial enumeration tests to determine bioburden in non-sterile pharmaceutical products, medical devices and raw materials.
  • USP 62
    USP 62 focuses on testing for specified microorganisms, providing an additional layer of microbial safety for non-sterile products.
  • EN 14683
    This European standard sets the requirements for bacterial filtration efficiency (BFE) of medical face masks, ensuring their effectiveness in preventing the spread of infections.
  • FDA guidelines
    We ensure that our bioburden testing services comply with all relevant FDA requirements, particularly for pharmaceutical and medical device manufacturers.

With MIS, you can rest assured that your products will meet or exceed all relevant regulatory standards to protect your brand reputation and keep your consumers safe.

Industries we serve

Our bioburden testing services address a wide array of industries that require stringent quality control and microbial monitoring to ensure the safety and compliance of their products. We provide services to the following industries:

  • Pharmaceuticals
    Bioburden testing is a key part of ensuring the safety and efficacy of pharmaceutical products. Manufacturers can rest assured that their products are safe and free from harmful microorganisms by conducting bioburden tests, which help in the early detection of contamination.
  • Medical devices
    Medical devices, particularly those that are intended for invasive use, must be free from harmful microorganisms. Bioburden testing can assist manufacturers in ensuring that their devices meet the required sterility requirements and are safe for patient use.
  • Cosmetics and personal care
    Bioburden testing is one of the most significant aspects of ensuring product safety in cosmetic and personal care industries, as most of these products are applied to sensitive body parts, such as skin and eyes.

Regardless of the industry, bioburden testing services available at MIS provide critical data to substantiate product safety and compliance with regulatory standards.

Why Choose Us?

By choosing MIS for your bioburden testing services, you are partnering with a select team that focuses on precision, reliability and speed. Here are a few reasons why our clients trust us for their microbial testing needs:

  • Expertise
    We have been continuously performing microbial testing for years and along the way, we have acquainted ourselves with newly updated techniques and standards for bioburden testing. We stay up to date with industry advancements to ensure we are offering the best possible service.
  • State-of-the-art laboratory
    Our laboratory is equipped with the latest technologies, which help us provide highly accurate and reproducible results. Strict quality control processes ensure tests are run at the highest possible standard.
  • Fast turnaround times
    We realise that time is critical to your operations. Our streamlined processes ensure that your bioburden test results are provided promptly without compromising quality.
  • Accredited methodologies
    Our bioburden testing methods are performed according to international standards, including ISO 11737 and USP guidelines, to ensure your products meet regulatory requirements.
  • Customer-focused approach
    Building long-term partnerships with our clients is paramount to us. Our team works closely with clients to understand their specific needs and offers personalized solutions to ensure the success of the testing program.
  • Comprehensive reporting
    We provide detailed reports that not only present the results but also offer insights and recommendations based on your product’s specific requirements. This helps you make informed decisions about product development and quality control.

Our commitment to quality and customer satisfaction differentiates us from various service providers within the industry. Contact us today to learn more about how our bioburden testing services can benefit your organization.

Frequently Asked Questions

What is textile testing?
Textile testing is the process of assessing the physical, mechanical and chemical properties of textiles in addition to performance testing, colorfastness testing and antimicrobial efficacy testing. This ensures that they meet specified standards and quality criteria.
Why is textile or fabric testing important?
Textile testing is important to ensure the quality and safety of textile products. It helps manufacturers meet industry standards, regulatory requirements and customer expectations.
How does antimicrobial clothing work?
Antimicrobial clothing is designed to inhibit the growth of microorganisms such as bacteria, fungi and viruses by incorporating antimicrobial agents into the fabric.
What is antimicrobial clothing?
Antimicrobial clothing refers to garments that have been treated with antimicrobial agents to reduce or eliminate the presence of microorganisms.
What are the common industry standards for textile testing labs?
Textile testing labs generally adhere to some of the common industry standards such as ASTM, ISO, AATCC and British Standards.

Ready to test your product?

Microbe Investigations Switzerland