Arm in Cage Mosquito Repellent Test

The Arm-in-Cage test is a standard test method used to evaluate the efficacy of mosquito repellents under laboratory conditions.

This test is applicable for topical mosquito repellents (cream, lotions, and spray formulations) and impregnated textiles.

This mosquito-repellent Arm-in-Cage test takes 3-4 weeks to complete.

The effectiveness is tested by applying the repellent to a volunteer’s forearm and exposing it to mosquitoes in a cage. The test measures the time until the first bite or landing, known as complete protection time (CPT).

Mosquito repellents work by masking human odors or emitting substances that mosquitoes find unpleasant, thus preventing them from landing and biting.

Mosquitoes are selected based on the species relevant to the geographic area and the target market. Species like Aedes, Anopheles, and Culex are typically used.

Yes, the results from these tests can be used for regulatory approval, provided that standard guidelines from organizations like the WHO or EPA are followed during testing.

The repellent should be spread evenly on the volunteer’s forearm. The amount and application method should follow the specified guidelines in the test protocol and manufacturer’s instructions.

Yes, this test can evaluate long-term effectiveness by monitoring the protection time (the duration from application until the time when repellent becomes ineffective).

Generally, five to ten volunteers are involved in arm-in-cage tests for product registration, while initial product development might use fewer participants.